Businesses For Sale in South Dakota

South Dakota

This long time agricultural manufacturer focuses on livestock equipment used in cattle handling and day-to-day agricultural operations. The Company serves core agricultural end markets with a...

$1,800,000

South Dakota

Established and well-regarded mosquito control business serving a loyal residential and commercial customer base in a growing regional market. The company provides recurring seasonal treatment...

$325,000

South Dakota

This established neighborhood bar is a local favorite and known as the area's go-to gathering spot, offering a comfortable atmosphere, loyal staff, and a strong customer following. The business...

$600,000

South Dakota

This is a rare opportunity to make an offer to acquire a long-established assisted living facility in Eastern South Dakota. The business has been thoughtfully built and meticulously maintained over...

Not Disclosed

South Dakota

Put your skill set to work in this high demand, daytime focused drive thru and take out coffee shop with a large selection of specialty drinks and handcrafted sandwiches. Strong sales of $600,000...

$475,000

South Dakota

This is a great opportunity to acquire an established and profitable dessert franchise. The business is offered turn-key, and is located in a high traffic corridor in a growing city. Seller and...

$499,500

South Dakota

For over 60 years, this beloved family restaurant and catering business has been a cornerstone of Northeastern South Dakota. Dine-in services operate daily, along with take-out and catering orders....

$300,000

Doland, SD

Dakota Convenience Store sits alongside US Hwy 212 in Doland SD near the crossroad with SD Hwy 37, situated in the finest pheasant hunting area in all of SD. The fueling system, USTs, Dispensers,...

$700,000

Willow Lake, SD

DAKOTA CONVENIENCE STORE - PREMIER HUNTING & FISHING DESTINATION Established convenience store operation in Willow Lake, SD, strategically positioned in northeast South Dakota's premier hunting and...

$700,000

Watertown, SD

Well-established fitness center with 300+ members. Located in a high-visibility area, the gym benefits from strong local recognition and an excellent reputation, including near 5-star reviews on...

$80,000

Minnehaha County, SD

For sale is a long-time daycare business consisting of two well-established centers strategically located in high-growth, family-friendly areas. This business cares for a wide range of children, from...

$400,000

South Dakota

This established manufacturing business produces high-quality agriculture trailers, custom aluminum exterior products and precision laser-cut components. They offer full custom design capabilities,...

$16,900,000

Minnehaha County, SD

This premier publication has been producing print and online content, promoting the people and places in their region, and growing their brand for nearly 20 years. The content spans lifestyle, food &...

$450,000

South Dakota

This business generates $144,021 (2025) in Seller’s Discretionary Earnings on ~$400K annual revenue and is well-known in the area for quality work and long-standing customer relationships. With over...

$250,000

Gregory, SD

Positioned along well-traveled Highway 18 in Gregory, SD, the Gray House Motel presents a rare opportunity to acquire a highly visible, income-producing hospitality property with strong community...

$650,000

South Dakota

Rare opportunity to own a consistently profitable real estate home-staging business that is highly respected, well organized, and has a proven successful track record; as a result, it has experienced...

$325,000

Sioux Falls, SD

Rare opportunity for this niche specialty excavation company that has a long-term excellent reputation within the SE South Dakota region. The company has earned its’ reputation for their dependability...

$850,000

Pennington County, SD

This well-know and profitable coffee shop has built a loyal and quality customer base for over a decade. Now, the owner is looking for the right buyer to continue to serve the customer base, and take...

$179,000

South Dakota

This locally owned and operated flooring company has been serving western South Dakota for nearly three decades. • Highly reputable, known for craftsmanship and customer service. • Diverse & loyal...

$199,000

Fall River County, SD

Here is an opportunity to operate your own franchise without having to start from scratch! Be part of a family of franchisees regionally and nationwide selling breakfast, lunch, dinner, catering and...

$680,000

South Dakota

A rare opportunity to acquire a large-scale FedEx Ground Linehaul operation in South Dakota, featuring four assigned team runs and three assigned solo runs. The team runs average approximately 4,500...

$4,000,000

South Dakota

This center provides high-quality before and after school care designed specifically for school-aged children. This center understands the importance of a safe, engaging environment that supports both...

$210,999

Union County, SD

Relocate this business to your location. An established operation offering a diverse range of high-demand vehicle upgrades and aftermarket solutions. With a proven track record and a loyal auto...

$499,000

Minnehaha County, SD

Niche sales and service business, based off monthly service contracts, currently over 200 monthly customers and growing. Business also has a wholesale division should a new owner look to continue that...

$620,000

Howard, SD

Howard Auto Clinic is a long-standing, highly trusted auto repair business serving Howard, SD and the surrounding area for decades. Known for dependable workmanship and strong local loyalty, the shop...

$425,000

Lincoln County, SD

An opportunity is available to acquire an established, fully operational fitness gym in a strong regional market. The business offers structured training programs supported by a proven operating model...

$375,000

South Dakota

The Company is a family-owned automotive service, parts, and repair business with deep roots in the community. The Company offers a comprehensive suite of automotive services and parts tailored to...

Not Disclosed

South Dakota

Headquartered in Southeast South Dakota, this business has proudly been the region’s leader in high-quality flags, flagpoles, and applique banners for over 40 years. Known for their craftsmanship and...

$210,000

South Dakota

This is your chance to own a well-established automobile dealership with a strong truck presence and licensing to sell in both South Dakota and Nebraska. With a large geographic sales footprint and...

$750,000

Sioux Falls, SD

Seize a rare opportunity to acquire a popular boutique fitness franchise location in Sioux Falls. Established in a prime retail plaza anchored by Walmart on West 85th Street, this Orangetheory Fitness...

$500,000