Businesses For Sale in South Carolina

Mount Pleasant, SC

Rare opportunity to acquire an established upscale-casual Italian restaurant + wine bar in one of Mount Pleasant’s most desirable commercial areas. The business generates over $3.0M in annual revenue...

$995,000

Charleston, SC

This investment opportunity represents a rare chance to acquire a high-performance, tech-integrated automated retail enterprise strategically located in the heart of Charleston, South Carolina. Since...

$224,000

Beaufort County, SC

HS Listing ID-70659 Long-standing commercial laundromat established in 2005, serving residents throughout Beaufort County, SC. The business operates as a fully self-service laundromat with...

$1,450,000

Myrtle Beach, SC

Haircuts and styling for men, women and children. Hair relaxers, perms, conditioning treatments and retouching as well as waxing services....

$49,000

Blacksburg, SC

The Early Education and Youth Development team has brought to market the operations and real estate of a turnkey childcare center in Cherokee County, SC. This offering features a licensed capacity of...

$1,475,000

South Carolina

This well-established landscaping contractor has built a thriving operation serving commercial and residential clients across the fast-growing Coastal SC region. With nearly $2.8M in revenue and...

$1,100,000

Mauldin, SC

This well-established local commercial cleaning business is part of a highly acclaimed and respected national franchise brand. We service large corporate accounts with contracts in place. This...

$17,490

Greenville, SC

Well-established fast-casual franchise pizza restaurant located in a high-traffic retail corridor in Greenville, SC. Operating since 2011, this location benefits from strong visibility, consistent...

$115,000

Sumter, SC

Turnkey Men & Boys Clothing Store for Sale – Sumter, SC (Includes Real Estate) Opportunity Highlights: Established men’s and boys apparel store with strong customer base For sale with real estate...

$449,000

Available in South Carolina

Different from other senior care franchises because we employ seniors, so fewer staffing issues! Home office. Low start-up costs. Non-medical. You can serve your seniors in about 8 weeks.

$75,000

Myrtle Beach, SC

Price Reduction . . . $80,000!!! Upscale Area and Clientele. Nice Boutique Liquor Store. (2) Year Old Location. Attractive Storefront, Good Signage and Parking. Located in a Busy Shopping Complex with...

$150,000

Myrtle Beach, SC

Enjoy a relaxed coastal vibe in a casual, second-floor spot on the Boardwalk known for its ocean views, fresh seafood and cocktails, offering a laid-back atmosphere for lunch, dinner or drinks with...

$499,000

Colleton County, SC

Excellent Reputation | Consistent Cash Flow Built over three decades on trust, reliability, and word-of-mouth referrals, this heating and air service business offers a dependable stream of income and...

$800,000

Hilton Head Island, SC

One of the BEST Asian restaurants on Hilton Head. Dinning room, bar seats, TV's with outdoor seating also,...

$500,000

Pickens County, SC

This is a compelling opportunity to acquire an established, revenue-generating transportation company with active routes, reliable drivers, and immediate cash flow. The business is currently operating...

$1,299,000

Charleston, SC

Opportunity to build and scale a modern, system-driven home services business in the heating and cooling sector — one of the most stable and essential industries in the country. This is not a job —...

$245,500

South Carolina

The company provides expert environmental cleanup and restoration solutions for microbial growth, water damage, infectious diseases, hoarding, biohazards, homeless encampments, hurricane shelters, and...

$200,000

Columbia, SC

This is a highly profitable seafood market located in South Carolina, known for its exceptionally strong sales and impressive net income. The business has built a loyal and consistent customer base...

$800,000

Lexington, SC

High-Volume Convenience Store, Deli and Gas Station in Lexington, SC (Lexington County) Exceptional opportunity to acquire a well-established, upscale branded fuel station located in the City of...

$399,000

Available in South Carolina

NerdsToGo is a leading technology services franchise dedicated to delivering expert IT support for homes and small businesses. With a nationwide network of certified “Nerds,” we specialize in providing fast, friendly, and reliable on-site, in-store, and remote tech solutions.

$80,000

Myrtle Beach, SC

A Home-based custom laser engraving business. Home decor, custom signs, keychains, ornaments, magnets etc. Work at your own pace....

$59,000

Myrtle Beach, SC

Established property maintenance company serving the Myrtle Beach commercial real estate market through comprehensive bulk service offerings. The business operates under long-term, auto-renewing...

$3,650,000

Myrtle Beach, SC

This established seafood market represents a premier business opportunity in Myrtle Beach's thriving commercial landscape. The operation has demonstrated consistent performance as a dominant market...

$1,000,000

South Carolina

This is not a food business. It is a brand — with proprietary recipes, a trademarked identity, a vetted supplier network, and a newly launched product line that hit the market to immediate demand....

$200,000

Charleston, SC

This offering is a new vended laundry project package for a 3,500-square-foot free-standing location and includes brand new Speed Queen laundry equipment and a comprehensive installation/build-out...

$899,000

Charleston, SC

Located in the heart of the city's main shopping and dining district, you have no shortage of foot traffic and visibility here! Great space with high ceilings and lots of light. This is an ideal spot...

$350,000

Greenville, SC

This premium chocolate and fresh fruit gift delivery business offers a unique opportunity to acquire a streamlined, profitable operation with strong regional coverage across Greenville, Columbia, and...

$375,000

Beaufort County, SC

This is a rare one. A multi-revenue retail and convenience store operating as the only commercial outlet on a private Lowcountry gated community — serving vacationing families, seasonal residents, and...

$90,000

Greenville, SC

Own this second generation Restaurant for Sale in a prime Upstate South Carolina location within the Greenville market. This 2,300 square foot space offers seating for about 50 guests and is...

$79,000

Available in South Carolina

Altitude Trampoline Park is the premier family entertainment destination, bringing active family fun to the global communities it serves. As one of the world's largest family entertainment franchises, the brand has grown to more than 85 locations open or in development across 29 states and four countries.

$400,000

Clemson, SC

Buy this profitable Restaurant for Sale in South Carolina located near Greenville with $1,554,884 in annual sales and $177,259 in verified Owner Benefit. Offered by We Sell Restaurants, this...

$449,000

Murrells Inlet, SC

One of the nicest Pizza Restaurants in the area known for it's authentic New York-style pizza, Italian dishes, sandwiches and calzones. Dine-in, takeout, delivery and catering options....

$279,000

Charleston County, SC

Full-service lawn, garden equipment dealer, trailer and tractor dealer. Original owner of 36 years is ready to retire presenting a terrific opportunity for the next owner. Along with full product...

$799,000

Columbia, SC

A twenty-year-old, well-established HVAC business serving residential clients. The client book consists of 1100 repeat business customers. This HVAC business employs full-time and subcontracted...

$1,500,000

Available Nationwide

Send Me a Pro is the first Home Services Platform Franchise, enabling you to aggregate multiple home services under one franchise.

$49,599

Charleston County, SC

Established youth music education business serving families in the greater Charleston area. The business offers a range of music instruction and enrichment programs, including private lessons,...

$275,000

Enoree, SC

Incredible Opportunity! Owner must sell!! Prime location with strong growth potential. Rare opportunity to own both a convenience store and liquor store with low overhead and great traffic. Gross...

$70,000

Mount Pleasant, SC

Established Poke and Acai Restaurant - Market at Oakland, North Mount Pleasant, SC This turnkey food service operation represents a prime opportunity to acquire an established poke and acai bowl...

$155,000

Hartsville, SC

2.7 + Million in sales! $391,000 in owner benefits! An outstanding Restaurant for Sale is available to acquire a successful full service steak and seafood restaurant along with the valuable real...

$2,100,000

Clemson, SC

This Liquor Store for sale is an established 25 year old business, in a great location. Profitable from day one. The owner is ready to retire. Sale price includes the real estate & inventory....

$449,900

Charleston, SC

This established business provides a streamlined way to capitalize on growing residential and commercial property maintenance demand—without requiring the owner to have a skilled-trade background....

$127,500

Spartanburg County, SC

Just outside of Woodruff SC in one of Spartanburg County's fastest growing Area's. A diner style restaurant serving Burgers, Hot dogs, and Sandwiches. Only open Monday-Friday Lunch and Dinner. If an...

$349,000

Greenville, SC

Turnkey Eatertainment Venue – Bowling, Golf Simulators & Games | $775K Sales Restaurant and entertainment investors: this is a rare opportunity to acquire a fully built family entertainment center and...

$795,000

Greenville, SC

This plumbing company doesn't just handle pipes... they can fix HVAC systems too! This is a great 2-in-1 deal that gives a buyer the best of both worlds. Handle both pain points for homeowners by...

$674,900

Available Nationwide

Once Upon A Child buys and sells gently used and new children's clothing, toys, equipment and more! With over 415 stores open in North America we are the nations largest chain of children's resale stores.

$90,000

Fort Mill, SC

Own this Pizza Franchise for Sale in Fort Mill, South Carolina, and step into a proven delivery and carryout concept designed for speed and consistency. This second generation restaurant is fully...

$75,000

North Myrtle Beach, SC

A seasonal, service-based, delivery-only beach gear rental business with low overhead. It's proven and profitable requiring low owner involvement with dependable cash flow and a repeat customer base....

$79,000

Greenville, SC

Business consistently gets excellent reviews. Multiple income streams from both grooming and accesory sales. 2025 sales up 55% vs. 2024. Still a new business with a great location. Average Unit Volume...

$235,000

Spartanburg, SC

Pizzeria for sale in the heart of Spartanburg. This is a beautifully built out pizza restaurant! Been established for over 7 years. Has all the equipment you need to be a successful operator. 3200 sq...

$199,000

Greenville, SC

Buy this Restaurant for Sale in Greenville, South Carolina, and step into a fully built out, second generation space with a full bar and inviting outdoor patio. Offered by We Sell Restaurants, this...

$150,000

Greenville, SC

Discover an exciting Franchise for Sale, offering a structured and supported path to ownership within a recognized brand. This opportunity allows you to step into an established operation with defined...

$125,000

Indian Land, SC

Own this Franchise for Sale in Indian Land, South Carolina, a fully built out second generation restaurant space with patio seating and a polished interior. Offered by We Sell Restaurants, this...

$99,000

Columbia, SC

Imagine stepping into a thriving HVAC business that's been serving the community for over a decade. You'll love the stability this established operation brings - with loyal customers who trust the...

$635,000

Horry County, SC

This well-established pool and spa business has been serving the community for over 16 years, building a loyal customer base and a strong reputation in the industry. Specializing in pool and spa...

$1,690,000

Available in South Carolina

Business coaching is a $7.5 billion industry in the United States. Turn your passion for business success into a successful Growth Coach franchise.

$50,000